How do active pharmaceutical ingredient manufacturers handle harmful substances?

active pharmaceutical ingredient manufacturers mainly handle harmful substances through the following methods:
waste gas treatment
The volatile organic compounds (VOCs), active pharmaceutical ingredients, and odorous substances generated during the production process need to be treated through the following processes:
Collection system: Install a gas collection hood or collection device to centrally treat exhaust gas and avoid unorganized emissions.  ‌
Preprocessing: Using dust removal, dehumidification and other technologies to remove particulate matter and moisture, improving subsequent processing efficiency.  ‌
Core processing technology:
Condensation recycling: Recycling organic solvents (such as ethanol) to achieve resource recycling.  ‌
Adsorption method: using activated carbon and other materials to remove VOCs and harmful substances.  ‌
Combustion method: Organic matter is converted into carbon dioxide and water through direct combustion or catalytic combustion.  ‌
Biological method: using microorganisms to degrade low concentration organic matter.  ‌
waste water treatment
Pharmaceutical wastewater contains toxic and harmful substances (such as heavy metals, aromatic compounds, etc.), requiring special processes:
Pre treatment: Remove suspended solids and sediment, regulate water quality fluctuations.  ‌
Deep processing: Using chemical or biological methods to decompose recalcitrant organic matter to ensure compliance with emission standards.  ‌
Nanofiltration membrane technology
Nanofiltration membrane can remove impurities, heavy metal ions, and harmful substances from raw materials, ensuring the purity of the formulation. Its advantages include:
No need for high temperature and chemical reactions, low energy consumption, and simple operation.  ‌
High degree of automation, reducing manual intervention and improving production efficiency.  ‌
Environmental compliance
Emission monitoring: Real time monitoring of exhaust gas/wastewater emission indicators to ensure compliance with environmental regulations (such as VOCs emission limits generally set at 150mg/m ³).  ‌
Source control: Implement unorganized emission control in material storage, feeding, and other processes.  ‌